TNPSC Thervupettagam

Kindlins - Adapter Proteins

August 10 , 2024 18 hrs 0 min 23 0
  • Kindlins are the adapter proteins that exist inside the cells attached to the cell membranes of almost all types of cells in vertebrates.
  • This protein is central to many signalling pathways, targeting it could lead to new cancer treatments that address multiple aspects of the disease at once.
  • Kindlins may undergo mutations under the influence of innumerable chemical and physical carcinogens like nicotine, ultraviolet rays and many more.
  • Mutated Kindlin can potentially disrupt global mechanical homeostasis within cells.
  • Therefore, understanding the consequences of genetic alterations in Kindlins holds the key to unravelling the intricate mechanisms leading to the growth of cancer cells.

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