Transcription factors are special proteins that help read the information in our DNA.
They attach to the specific regions of the DNA and start a process called the transcription, which copies genetic information from DNA to RNA.
New research found that the fate of a gene being transcribed depends on the location of the transcription factor binding site relative to the location where transcription begins.
This provides insights into how different spatial arrangements of the same transcription factors can have different effects.
The findings can “help filter and refine genomic tools and algorithms that predict gene expression”.