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CAR-T therapy
February 7 , 2019
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- An 11-year-old Indian-origin boy has become the first patient to receive a pioneering new cancer therapy (CAR-T) by the UK's state-funded National Health Service.
- CAR-T is a personalized form of cancer treatment.
- CAR-T involves removing immune cells and modifying them in a laboratory so they can recognize cancer cells.
- Immunotherapy is a treatment that uses your body's own immune system to help fight cancer.
- Blood taken from patient and the white blood cells are separated out in the first stage, the rest of the blood being returned to the patient.
- Then harmless virus is used to insert genes into T-cells, a special type of immune cell.
- These genes cause the T-cells to add a hook on to their surface, known as a chimeric antigen receptor (CAR).
- These engineered CAR-T cells - programmed to recognize and destroy the patient's cancer cells - are multiplied in huge numbers and then infused back into the patient.
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