TNPSC Thervupettagam

Drug for Alzheimer’s treatment

March 3 , 2021 1239 days 876 0
  • The scientists have designed a set of novel small molecules that could disrupt the mechanism.
  • Through it, the neurons become dysfunctional in Alzheimer’s disease.
  • They are from Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR).
  • The molecule (molecule TGR63) could reduce the toxicity of Amyloid Beta (Aβ) toxicity.
  • It is a potential drug candidate to halt or cure the leading cause of dementia (70-80%) worldwide.
  • Alzheimer's disease is an irreversible, progressive brain disorder.
  • It slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks.

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