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Endogamy - harmful genetic variants
August 8 , 2023
469 days
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- A new study has found higher frequency of homozygous genotypes in South-Asian populations, most likely as a result of caste, endogamy, and consanguineous sexual unions.
- Such a frequency could lead to higher risk of genetic disorders.
- South-Indian and Pakistani subgroups were estimated to have a high degree of inbreeding.
- The study found stark genetic differences between people from different regions of the subcontinent.
- Humans typically have two copies of each gene.
- When an individual has two copies of the same variant, it is called a homozygous genotype.
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