TNPSC Thervupettagam

Haemophilia A gene therapy

March 5 , 2024 265 days 356 0
  • India has conducted the first human clinical trial of gene therapy for ‘haemophilia A’ at Christian Medical College – Vellore.
  • Hemophilia is a group of conditions that impact the blood’s ability to coagulate, or clot.
  • Hemophilia occurs when an individual has low levels of certain proteins in the blood, known as clotting factors.
  • Hemophilia A and hemophilia B are the two main types of hemophilia.
  • Both conditions have similarities but are distinguishable by the genetic variation that causes the blood clotting problem.
  • People living with hemophilia A have a genetic variation in the F8 gene, which is responsible for producing blood clotting factor VIII.
  • Hemophilia B have a genetic alteration in the F9 gene, which results in the underproduction of blood clotting factor IX.

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