Kindlins are the adapter proteins that exist inside the cells attached to the cell membranes of almost all types of cells in vertebrates.
This protein is central to many signalling pathways, targeting it could lead to new cancer treatments that address multiple aspects of the disease at once.
Kindlins may undergo mutations under the influence of innumerable chemical and physical carcinogens like nicotine, ultraviolet rays and many more.
Mutated Kindlin can potentially disrupt global mechanical homeostasis within cells.
Therefore, understanding the consequences of genetic alterations in Kindlins holds the key to unravelling the intricate mechanisms leading to the growth of cancer cells.