TNPSC Thervupettagam

New Drug delivery method

October 4 , 2024 83 days 228 0
  • The Scientists have used a chitin synthesis fungicide, Nikkomycin, produced by the bacterial Streptomyces spp. to develop Nikkomycin loaded polymeric nanoparticles.
  • Chitin is the chief component of fungal cell walls and is absent in the human body.
  • The drug loaded nanoparticles were found to disrupt the growth of Aspergillus spp and found effective against fungal infection known as Aspergillosis.
  • The nano formulation developed was found to be free of cytotoxic and hemolytic effects.
  • The use of polymeric nanoparticles is the most advanced method of drug delivery.

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