The Scientists have used a chitin synthesis fungicide, Nikkomycin, produced by the bacterial Streptomyces spp. to develop Nikkomycin loaded polymeric nanoparticles.
Chitin is the chief component of fungal cell walls and is absent in the human body.
The drug loaded nanoparticles were found to disrupt the growth of Aspergillus spp and found effective against fungal infection known as Aspergillosis.
The nano formulation developed was found to be free of cytotoxic and hemolytic effects.
The use of polymeric nanoparticles is the most advanced method of drug delivery.