Scientists Jacques Dubochet, Joachim Frank and Richard Henderson won the 2017 Nobel Prize in Chemistry developing cryo-electron microscopy, which improves the imaging bimolecular activities of enzyme’s that causes disorders like Zika and Alzheimer's.
So far beams electrons were used with a technique known as transmission electron microscopy (TEM) or scientists employed a method known as x-ray crystallography in which x-rays are scattered as they pass through samples, creating patterns that can be analysed to reveal the structure of molecules.
Structure of atoms cannot be studied when molecular reaction is being carried out.
Cryo-Microscopy operates based on principle of 3D imaging.
The ultra-sensitive imaging method allows molecules to be flash-frozen to cryogenic temperatures (-150 degree Celsius ). Microscopic parts of the cell are studied in their natural form, without the need for Microscopic Strain Dye.
This invention will lead to development in fields of bio chemistry, development of pharmaceuticals and pave way for developing medicines to Zika , Alzheimer’s and other disorders.