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Pantranscriptome
January 26 , 2023
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- Pantranscriptome is s combination of transcriptome and a pangenome.
- It contains genetic material from a cohort of diverse individuals, rather than just a single linear strand.
- RNA’s most commonly recognized function is to translate DNA into proteins.
- But scientists now understand that the vast majority of RNA does not make proteins, but instead can play roles such as influencing cell structure or regulating genes.
- The entire RNA landscape is known collectively as the transcriptome.
- The pantranscriptome-concept builds on the emerging concept of “pangenomics” in the genomics field.
- Using a pangenome allows researchers to compare an individual’s genome to that of a genetically diverse cohort of reference sequences all at once, sourced from individuals representing a diversity of biogeographic ancestry.
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