TNPSC Thervupettagam

RAD51 Protein

March 13 , 2024 117 days 216 0
  • Researchers observed that RAD51 temporarily binds to the newly synthesized DNA.
  • Thus, RAD51 prevents genomic duplications that could arise from re-activated origins.
  • Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent.
  • This means that millions of times a day a biochemical wonder takes place in the body: the copying of the DNA molecule.
  • It is a high-precision job carried out by specific proteins and includes systems to protect against potential errors that could lead to diseases such as cancer.
  • When a region of DNA is over-replicated, breaks are created in the molecule, and the likelihood of a cancer-related gene being over-expressed increases.
  • Therefore, avoiding excess replication prevents DNA damage and reduces the chances of oncogenes being amplified.

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