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Sixth Person cured from HIV
July 27 , 2023
488 days
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- A sixth person with HIV, being referred to as the Geneva patient, has likely been cured of HIV after receiving a stem cell transplant for leukaemia.
- The level of virus in his blood remained undetectable 20 months after his antiretroviral therapy was discontinued.
- This patient underwent a stem cell transplant in 2018 for an aggressive form of leukaemia.
- Twenty months later, his tests did not find any viral particles, latent reservoirs of the infection, or elevated immune response against the virus.
- All the six patients who have achieved HIV remission so far needed the stem cell transplantation for treatment of their cancers.
- In the first five cases, however, the treatment teams specifically looked for donors with CCR5 delta 32 mutation that is associated with lower risk of HIV.
- HIV lowers immunity in infected individuals by attacking the CD4 immune cells.
- Berlin patient, became the first person to overcome HIV after two stem cell transplants in 2007 and 2008.
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